Add-On Lipid Drugs for ASCVD After Statins, by Guideline
LDL-C still high on statins or ezetimibe? Compare add-on lipid-lowering drug options and where each fits current ACC/AHA secondary prevention guidance.
Cardiovascular Disease: Diagnosis and Treatment
13 source-based articles maintained by the HealthRX.com Editorial Team.
13articles
2topic areas covered
Jul 31, 2026latest review
Cardiovascular Disease: Diagnosis and Treatment library
Showing 13 of 13 clinical reviews.
Established Cardiovascular Disease and Mental Health: The Clinical Overlap
Depression, anxiety, and PTSD occur at 2-3x the general population rate in patients with established cardiovascular disease. Evidence-based screening and treatment reduce both psychiatric burden and recurrent MACE.
Established Cardiovascular Disease Guidelines Compared: ADA, AACE, Endocrine Society, and More
Compare current ADA, AACE, Endocrine Society, and ACC/AHA recommendations for LDL cholesterol, blood pressure, GLP-1 therapy, and established heart disease.
Established Cardiovascular Disease: Common Comorbidities and Overlap
A guide to the most common conditions that co-occur with established cardiovascular disease, how they interact, and what the evidence says about managing them together.
Established Cardiovascular Disease: Emerging Mechanism Research
A review of mechanistic research beyond LDL-lowering in established cardiovascular disease, covering inflammation, clonal hematopoiesis, gut microbiome signaling, Lp(a), and GLP-1 receptor agonists, with notes on evidence strength and what remains unproven.
Established Cardiovascular Disease: Global Prevalence and Trends
A overview of established cardiovascular disease worldwide, covering prevalence data, regional burden, mortality trends, and guideline-based risk context for patients and providers.
Established Cardiovascular Disease: Open Controversies in the Field
A deep dive into the most contested clinical questions in established cardiovascular disease, from optimal LDL targets to the role of GLP-1 agonists, polypharmacy debates, and residual inflammatory risk.
Established Cardiovascular Disease: Rare and Atypical Presentations
A guide to rare and atypical presentations of established cardiovascular disease, including silent MI, vasospastic angina, Kounis syndrome, cardiac syndrome X, MINOCA, and Takotsubo cardiomyopathy, with an evidence-boundary map and a bedside screening framework.
Exercise Prescription for Established Cardiovascular Disease
Evidence-based exercise protocols for patients with established cardiovascular disease, including post-MI, stroke, PAD, and coronary artery disease. Covers cardiac rehab phases, intensity targets, and safety monitoring.
Genetics and Family History in Established Cardiovascular Disease
How inherited risk shapes outcomes in patients with established cardiovascular disease, from polygenic risk scores to familial hypercholesterolemia screening and targeted pharmacotherapy.
Nutrition and Lifestyle Protocols for Established Cardiovascular Disease
Evidence-based nutrition and lifestyle protocols for adults with established cardiovascular disease, including post-MI, stroke, PAD, and symptomatic CAD. Covers dietary patterns, physical activity targets, weight management, and GLP-1 therapy based on current AHA, ADA, and ACC guidelines.
Racial and Ethnic Disparities in Established Cardiovascular Disease
Cardiovascular treatment gaps by race and ethnicity: primary studies, stroke data, secondary prevention and practical ways to improve access and follow-up.
Stopping Treatment Safely With Established Cardiovascular Disease
A guide to safely discontinuing or tapering cardiovascular medications in patients with established CVD, including what is well established, what is plausible but unproven, and when to get urgent care.