Lisinopril and Atorvastatin Interaction: Safety, Monitoring, and Clinical Evidence
Lisinopril and atorvastatin have no clinically significant interaction: separate metabolic pathways and need no dose change. Monitor potassium in CKD.
Lisinopril: Drug Interactions
21 source-based articles maintained by the HealthRX.com Editorial Team.
21articles
3topic areas covered
May 26, 2026latest review
Lisinopril: Drug Interactions library
Showing 21 of 21 clinical reviews.
Lisinopril and Diphenhydramine Interaction: Safety, Risks, and What to Monitor
Can you take lisinopril with diphenhydramine? What is established, what is plausible but unproven, and what a pharmacist should verify before combining an ACE inhibitor with a first-generation antihistamine.
Lisinopril and Estradiol HRT Interaction: Safety, Risks, and Clinical Guidance
Can you take lisinopril with estradiol hormone replacement therapy? Learn about the drug interaction profile, monitoring requirements, and evidence-based clinical guidance.
Lisinopril and Finasteride Interaction: What Patients and Clinicians Need to Know
A guide to the lisinopril and finasteride drug interaction: mechanism, severity, monitoring parameters, and patient counseling for safe co-administration.
Lisinopril and Gabapentin Interaction: What Patients and Clinicians Need to Know
How lisinopril (an ACE inhibitor) and gabapentin interact through kidney function rather than metabolism, what monitoring is warranted, and what remains unverified in commonly cited claims about this combination.
Lisinopril and Hormonal Contraceptives: Drug Interaction Guide
Can you take lisinopril with birth control pills, patches, or rings? A guide to the interaction between ACE inhibitors and hormonal contraceptives, including mechanism, monitoring, and dose adjustments.
Lisinopril and Levothyroxine Interaction: What Patients and Clinicians Need to Know
A guide to the lisinopril and levothyroxine drug interaction, covering absorption timing, monitoring of thyroid and blood-pressure parameters, and safe co-administration strategies.
Lisinopril and Metformin Interaction: Safety, Risks, and Monitoring
Metformin and lisinopril can be taken together safely in most patients. There is no direct interaction, but kidney function still needs regular monitoring.
Lisinopril and NSAIDs (Ibuprofen, Naproxen): Drug Interaction Guide
Can you take Aleve (naproxen) with lisinopril? Usually no: naproxen's long half-life raises kidney and potassium risk. Acetaminophen is a safer choice.
Lisinopril and Opioids (Oxycodone, Hydrocodone, Tramadol): Interaction Guide
Clinical review of interactions between lisinopril and opioids including oxycodone, hydrocodone, and tramadol. Covers mechanisms, blood pressure effects, monitoring, and dose adjustments.
Lisinopril and PPIs (Omeprazole, Pantoprazole): Interaction Explained
Can you take lisinopril with omeprazole or pantoprazole? A board-certified clinical review of the pharmacokinetic and pharmacodynamic interaction, severity rating, monitoring, and patient counseling points.
Lisinopril and Pregabalin Interaction: Safety, Risks, and What to Monitor
Can you take lisinopril with pregabalin? A clinical review of the interaction profile, shared side effects, monitoring parameters, and dose-adjustment guidance for patients on both medications.
Lisinopril and Progesterone HRT Interaction: What Patients and Clinicians Need to Know
A clinician-level review of the lisinopril and progesterone HRT interaction, covering mechanism, sedation overlap, blood pressure monitoring, and dose-adjustment guidance.
Lisinopril and Rosuvastatin Interaction: Safety, Monitoring, and What Prescribers Check
Can you take lisinopril with rosuvastatin? A guide covering pharmacokinetic data, monitoring requirements, and clinical evidence for this common drug combination.
Lisinopril and Sildenafil Interaction: What Patients and Clinicians Need to Know
A guide to the lisinopril and sildenafil drug interaction: mechanism, severity, real trial data, monitoring parameters, dose guidance, and patient counseling points.
Lisinopril and Simvastatin Interaction: Safety, Risks, and Monitoring
Can you take lisinopril with simvastatin? A clinician-grade review of the pharmacokinetic and pharmacodynamic profile, co-prescription safety data, monitoring protocols, and dose considerations.
Lisinopril and SSRIs (Sertraline, Escitalopram): Drug Interaction Guide
Can you take lisinopril with sertraline or escitalopram? A guide covering the pharmacology, risks, monitoring, and clinical evidence behind combining an ACE inhibitor with an SSRI.
Lisinopril and Tadalafil Interaction: Safety, Risks, and Clinical Guidance
Can you take lisinopril with tadalafil? A clinical breakdown of the pharmacodynamic interaction, blood pressure risks, and what to verify with a prescriber or pharmacist before combining them.
Lisinopril and Testosterone Interaction: What Patients and Clinicians Need to Know
A detailed clinical guide to the lisinopril and testosterone interaction, covering mechanism, cardiovascular risk, polycythemia, blood pressure monitoring, and dose management for TRT patients.
Lisinopril and Trazodone Interaction: Safety, Risks, and Monitoring
Can you take lisinopril with trazodone? A guide covering the pharmacodynamic interaction, hypotension risk, monitoring parameters, and dose-adjustment strategies.
Plavix and Lisinopril: Is It Safe to Take Together?
Yes, Plavix and lisinopril can be taken together safely. No direct drug interaction exists; they work through different pathways with no shared metabolism.