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As-needed benzodiazepine timing card for Mounjaro dose steps
A pocket record of each as-needed benzodiazepine dose in the weeks after starting or raising Mounjaro: when you took it, whether with food, how long it took to work, any vomiting, and whether you were tempted to redose. It shows your prescriber a timing pattern instead of a guess.
Your medicines
Benzodiazepine, strength and how often you may take it
What it is for
Mounjaro dose (mg) and injection day
Other sedating medicines or alcoholopioids, sleep medicines, pregabalin, drinks per week
Each as-needed dose
One line per dose. If it seems slow, write it down and call rather than taking another.
| Date and time taken | Weeks since the last Mounjaro increase | With food? | Minutes until it worked | Vomited soon after? | Drowsy or unsteady later? | Second dose taken? |
|---|---|---|---|---|---|---|
Label facts behind the card
- Mounjaro slows stomach emptying, which can affect absorption of medicines taken by mouth; the effect was largest after the first 5 mg dose and smaller after later doses.[1]
- In the Valium label, a meal moved diazepam's peak from 1.25 hours to about 2.5 hours.[2]
- Alprazolam (Xanax) normally peaks 1 to 2 hours after a dose.[3]
- Clonazepam's half-life is typically 30 to 40 hours.[4]
- Benzodiazepines with opioids can cause profound sedation, slowed breathing, coma and death.[4]
Get help now for
- Severe drowsiness or breathing problems, especially with an opioid, alcohol or another sedating medicine.[4]
- Vomiting or diarrhea that stops you keeping fluids down, since fluid loss can harm the kidneys.[1]
Ask before the next Mounjaro increase
- How long should I wait before deciding an as-needed dose has not worked?
- If I vomit soon after a dose, should I take another or wait?
- Would a scheduled dose or a different benzodiazepine suit me better while Mounjaro is being increased?
- Is it safe to drive on days I take both?
Sources for the facts on this sheet
- Eli Lilly and Company, via DailyMed. Mounjaro (tirzepatide) injection, for subcutaneous use: prescribing information and Medication Guide. Effective 2026-08-27. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d2d7da5d-ad07-4228-955f-cf7e355c8cc0
- Waylis Therapeutics LLC, via DailyMed. Valium (diazepam) tablets: prescribing information and Medication Guide. Effective 2026-10-06. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=260e2041-2bb3-482f-850e-b5d47a7bdbe6
- Viatris Specialty LLC, via DailyMed. Xanax (alprazolam) tablets: prescribing information and Medication Guide. Effective 2024-04-15. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bb5cf72e-3a41-41a8-9a38-80f974eca33f
- H2-Pharma, LLC, via DailyMed. Klonopin (clonazepam) tablets: prescribing information and Medication Guide. Effective 2025-12-01. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cfa0d79a-843c-4b88-95a1-e9511d649ca1
This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.