HealthRX.com · Printable medication review sheet
Eliquis stack check and bleeding log
Sort every product you take alongside apixaban into the label's groups, log any bleeding signs with dates, and keep a procedure plan with the time of your last dose. Bring it to the clinician who manages your anticoagulation.
Your apixaban
Dose and timesfor example 5 mg or 2.5 mg, twice daily
Why you take itatrial fibrillation, clot treatment, after hip or knee surgery
Age 80 or older, weight 60 kg or less, creatinine 1.5 mg/dL or moretick each that applies
Prescriber and phone number
Every other product, sorted by label group
| Product and daily amount | Strong P-gp and CYP3A4 inhibitor? | Strong inducer, such as St. John's wort? | Adds bleeding risk (aspirin, NSAID, SSRI or SNRI, another blood thinner)? | Prescriber told (date) |
|---|---|---|---|---|
Bleeding signs
| Date | Sign (bruising, gum or nose bleeding, red or black stool, pink or brown urine) | How long it lasted | Who you told |
|---|---|---|---|
Before a planned procedure
Procedure and date
Bleeding-risk level the surgeon gave
Date and time of the last apixaban dose
Supplements the surgical team has been told about
When and how to restart
Eliquis label points
- Combined P-gp and strong CYP3A4 inhibitors: the dose is cut by 50% on 5 mg or 10 mg twice daily, and the combination avoided on 2.5 mg twice daily.[1]
- Combined P-gp and strong CYP3A4 inducers, including St. John's wort: avoid.[1]
- Stop at least 48 hours before a procedure with moderate or high bleeding risk, or at least 24 hours before a low-risk one.[1]
- A missed dose is taken as soon as possible the same day; the dose is never doubled.[1]
- Stopping early without other anticoagulation raises the risk of clots.[1]
Call your provider or get medical help right away
- Unexpected bleeding or bruising, or bleeding that lasts a long time, such as unusual gum bleeding or frequent nosebleeds.[1]
- Bleeding that is severe or will not stop, red, pink or brown urine, or red or black, tar-like stools.[1]
For the clinician who manages your anticoagulation
- Does any product on my list fall into a group that changes my apixaban dose?
- Do I meet two of the criteria for the 2.5 mg dose?
- Before my procedure, how long before should my last dose be, and when do I restart?
- Should I pause NMN or NR around the procedure?
- Which bruising or bleeding should make me call now, and which can wait for my visit?
Sources for the facts on this sheet
- E.R. Squibb & Sons, L.L.C. (Bristol-Myers Squibb), via DailyMed. Eliquis (apixaban) tablets, tablets for oral suspension and Eliquis Sprinkle: prescribing information and Medication Guide. Effective 2025-04-17. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e9481622-7cc6-418a-acb6-c5450daae9b0
This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.