HealthRX.com · Printable medication review sheet
Rivaroxaban and longevity-supplement review
List every supplement you take alongside rivaroxaban, with your latest kidney result and the dose rules from the Xarelto label, so the clinician who manages your anticoagulation can judge the whole stack rather than NMN or NR alone.
Your anticoagulation
Why you take rivaroxabanatrial fibrillation, clot treatment, clot prevention after surgery, other
Dose and time of day, and whether you take it with a meal
Latest kidney result (creatinine clearance or eGFR) and its date
Body weight and age
Aspirin, other antiplatelets or anti-inflammatory painkillers (NSAIDs)
Any bleeding or unusual bruising so far
Supplement stack
The page's concern is the whole stack: quercetin and resveratrol act on CYP3A4 or P-gp in lab studies even though NMN and NR are not known to.
| Supplement | Amount per day | Date started | Why you take it | Prescriber told? (date) |
|---|---|---|---|---|
| NMN or NR | ||||
| Quercetin | ||||
| Resveratrol | ||||
| Berberine | ||||
| Fisetin | ||||
Xarelto label rules to check your routine against
- Take the 15 mg and 20 mg tablets with food; food raised exposure to the 20 mg dose (AUC) by 39%.[1]
- For atrial fibrillation: 20 mg once daily with the evening meal when creatinine clearance is above 50 mL/min, 15 mg once daily when it is 50 mL/min or lower.[1]
- Avoid medicines that are combined P-gp and strong CYP3A inhibitors (such as ketoconazole and ritonavir) or inducers (such as carbamazepine, phenytoin, rifampin and St. John's wort).[1]
- With creatinine clearance from 15 to under 80 mL/min, the label advises against adding combined P-gp and moderate CYP3A inhibitors such as erythromycin unless the benefit justifies the risk.[1]
- Before a procedure, rivaroxaban is stopped at least 24 hours ahead, on your prescriber's instruction. Never stop it on your own: stopping raises stroke risk.[1]
- Missed a once-daily dose: take it as soon as you remember the same day, then the next dose at the usual time.[1]
- The Medication Guide asks you to tell your doctor about all vitamins and herbal supplements, not only prescription medicines.[1]
Call your doctor or get medical help right away
- Bleeding that is severe, will not stop or keeps coming back: frequent nosebleeds, bleeding gums, unusually heavy periods, red, pink or brown urine, bright red or black tarry stools, coughing up blood, or vomit that looks like coffee grounds.[1]
- Headache, dizziness or weakness, or pain, swelling or new drainage at a wound.[1]
- After a spinal or epidural procedure: back pain, tingling or numbness in the legs, muscle weakness, or loss of bowel or bladder control.[1]
Questions for the clinician who manages your anticoagulation
- Is my kidney result recent enough to confirm my rivaroxaban dose?
- Does anything in my supplement stack act on CYP3A4 or P-gp, and should any of it go?
- Given my kidney function and other medicines, would an anti-Xa level after starting a supplement tell us anything useful?
- Should I pause NMN, NR or the rest of the stack before a planned procedure?
- Which bruising or bleeding should make me call you, and which can wait for my next visit?
Sources for the facts on this sheet
- Janssen Pharmaceuticals, Inc., via DailyMed. Xarelto (rivaroxaban) tablets and oral suspension: prescribing information and Medication Guide. Effective 2026-09-10. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=10db92f9-2300-4a80-836b-673e1ae91610
This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.