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HealthRX.com · Printable symptom log

Benzodiazepine while starting Wegovy: daily sleepiness, unsteadiness and falls record

List every sedating medicine you take, then score sleepiness and unsteadiness each day through a Wegovy dose step, with any fall, near-fall or extra as-needed dose. Bring it to the visit before the next dose increase.

Companion to “Wegovy and Benzodiazepines Interaction: What Patients and Prescribers Need to Know” · healthrx.com/interactions-wegovy/with-benzodiazepines · Facts checked 2026-10-19

Every sedating medicine

Benzodiazepine: name, dose, times a day or as needed
What it is foranxiety, panic, sleep, seizures, other
Opioids, muscle relaxants, sleep aids or sedating antihistamines
Alcohol: drinks in a usual week
Wegovy start date and current dose
Falls or near-falls in the past year

Each day of a Wegovy dose step

Score 0 for none, 1 mild, 2 moderate, 3 severe.

DateWegovy doseBenzodiazepine doses taken (extra as-needed?)Sleepiness 0 to 3Dizzy or unsteady 0 to 3Fall or near-fallDrove today?Nausea

What the two labels report

  • In clonazepam's panic-disorder trials, somnolence was reported by 37% (10% on placebo) and ataxia by 5% (0% on placebo).[1]
  • In Wegovy's adult weight trials, fatigue was reported by 11% (5% on placebo) and dizziness by 8% (4% on placebo).[2]
  • Benzodiazepines with opioids may cause profound sedation, slowed breathing, coma and death.[1]
  • Stopping clonazepam abruptly or cutting the dose fast can cause withdrawal that can be life-threatening.[1]
  • The Klonopin label advises avoiding alcohol.[1]

When to get help

  • Get emergency help right away for shallow or slowed breathing, breathing that stops, or excessive sleepiness, especially with an opioid, alcohol or another sedating medicine.[1]
  • On insulin or a sulfonylurea: dizziness, shakiness, sweating, confusion or drowsiness can be low blood sugar rather than the benzodiazepine; ask your healthcare provider how to recognize and treat it.[2]

Before the next Wegovy dose increase

  1. Is my sleepiness or dizziness score high enough to hold this dose step for longer?
  2. Am I taking more as-needed doses than before, and why?
  3. Should I avoid driving until I know how the combination affects me?
  4. If my sleep or anxiety improves, what would a gradual taper look like?
  5. Does a fall or near-fall change the plan?
Sources for the facts on this sheet
  1. DailyMed. Klonopin (clonazepam) tablets: prescribing information and Medication Guide. Effective 2025-12-01. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cfa0d79a-843c-4b88-95a1-e9511d649ca1
  2. Novo Nordisk, via DailyMed. Wegovy (semaglutide) injection, for subcutaneous use, and Wegovy (semaglutide) tablets, for oral use: prescribing information and Medication Guide. Effective 2026-06-18. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ee06186f-2aa3-4990-a760-757579d8f77b

This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.