HealthRX.com · Printable medication review sheet
SNRI on Zepbound: vomiting, missed-capsule and nausea-medicine record
Note your SNRI's name, form and daily time, then log any day when vomiting, a late or missed capsule, or a new nausea medicine came up during Zepbound dose steps. It keeps each label's swallowing, missed-dose and stopping instructions on one sheet to show the prescribers.
Your two medicines
SNRI name, strength and formduloxetine delayed-release or venlafaxine extended-release capsule
Time of day you take it, and with or without food
Zepbound dose now and injection day
Next planned Zepbound dose increase
Who prescribes each medicine, and their contact
Days with vomiting, a missed capsule or a new nausea medicine
| Date | Days since Zepbound injection | Vomiting: how many times, how soon after the capsule | SNRI capsule: on time, late or missed | Dizziness, headache, tingling or irritability | Nausea medicine taken |
|---|---|---|---|---|---|
Instructions from the labels
- Duloxetine: swallow the capsule whole, with or without meals. If a dose is missed, take it when remembered unless the next one is nearly due; never take two at once.[1]
- Venlafaxine XR: once a day with food at about the same time, swallowed whole with fluid, not divided, crushed or chewed.[2]
- Stopping duloxetine can bring dizziness, headache, nausea, diarrhea, tingling, irritability, vomiting, insomnia, anxiety, heavy sweating and fatigue; the label recommends a gradual reduction.[1]
- With venlafaxine, discontinuation symptoms became more frequent at higher doses and after longer treatment.[2]
- Zepbound slows stomach emptying and may change how pills taken with it are absorbed.[3]
Do not wait for the next appointment
- Agitation, confusion, fast heartbeat, sweating, fever, tremor, stiffness or muscle jerks, especially after a new medicine was added: contact your healthcare provider or go to the emergency room.[2]
- Nausea, vomiting or diarrhea that does not go away: tell your healthcare provider right away.[3]
- Severe stomach pain that will not go away, with or without vomiting: stop Zepbound and call your healthcare provider right away.[3]
For whoever prescribes the SNRI or Zepbound
- If I vomit soon after taking my capsule, should I take another one?
- Which anti-nausea medicine, if any, fits with my SNRI?
- Should one of these doses stay the same while the other one changes?
- What should I do if vomiting makes me miss more than one SNRI dose?
- Which of you should I call first if new symptoms start?
Sources for the facts on this sheet
- Solco Healthcare US, LLC, via DailyMed. Duloxetine delayed-release capsules, for oral use: prescribing information and Medication Guide. Effective 2025-12-21. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a105a648-6a97-4151-b9de-d7eac90a8f79
- Viatris Specialty LLC, via DailyMed. Effexor XR (venlafaxine extended-release) capsules, for oral use: prescribing information and Medication Guide. Effective 2023-08-15. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c848a5d8-ba94-4c84-80e3-0bf35fb8e32e
- Eli Lilly and Company, via DailyMed. Zepbound (tirzepatide) injection, for subcutaneous use: prescribing information and Medication Guide. Effective 2026-08-28. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=487cd7e7-434c-4925-99fa-aa80b1cc776b
This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.