HealthRX.com · Printable medication review sheet
MOTS-c vial handling and temperature-excursion record for the dispensing pharmacy
A one-page record of the exact preparation, how it was stored and what happened to it, built from this page's excursion list, so the pharmacy that made the vial can assess it instead of a generic rule.
The preparation as dispensed
Copy these from the label and pharmacy paperwork, not from a seller's website.
Dispensing pharmacy and phone number
Product name exactly as labeled
Form stated on the labelfree base, acetate, or not stated
Concentration, diluent and container
Lot number and beyond-use date
Storage range and light protection printed on the label
What happened to the vial
One line per event. Write "unknown" rather than guessing a temperature or a time.
| Date and time noticed | Highest and lowest temperature, and how it was measured | How long, and how many times | Sealed, mixed, or already punctured | Cloudiness, particles, color, leak or seal damage |
|---|---|---|---|---|
Before you call the pharmacy
- Vial set aside and not used until the pharmacy has assessed it
- Label, carton and any mixing instructions photographed
- Thermometer, fridge or shipping record saved if one exists
- Any change in how the solution looks written down, even if it now looks normal
Why a generic web rule cannot clear this vial
- FDA's July 2026 review reports ingredient storage statements that disagree: a certificate listing 2°C to 8°C for MOTS-c acetate, and a supplier listing -80°C for 2 years or -20°C for 1 year.[1]
- Neither form of MOTS-c is a component of an FDA-approved drug, so there is no FDA-verified expiration date to fall back on.[1]
- FDA notes that aggregates can form in formulated peptide products during storage or under stress conditions.[1]
- FDA does not verify the quality of compounded drugs before they are marketed.[2]
- FDA warns that a medicine may degrade when it is not stored according to its labeled conditions.[3]
Questions for the pharmacy that prepared it
- Was the beyond-use date set from a stability study of this exact preparation, or from a default limit?
- Does anything in your records cover the temperature and time I have written down?
- Should I return or discard this vial, and can it be replaced?
- Which salt form, diluent and container were used?
- Who should I contact if a vial looks normal but was left out of storage again?
Sources for the facts on this sheet
- U.S. Food and Drug Administration. FDA Briefing Document: MOTS-c-Related Bulk Drug Substances (MOTS-c (free base) and MOTS-c acetate), Pharmacy Compounding Advisory Committee, July 23-24, 2026. Accessed 2026-10-19. https://www.fda.gov/media/193347/download
- U.S. Food and Drug Administration. Compounding and the FDA: Questions and Answers. Accessed 2026-10-19. https://www.fda.gov/drugs/human-drug-compounding/compounding-and-fda-questions-and-answers
- U.S. Food and Drug Administration. Expiration Dates - Questions and Answers. Accessed 2026-10-19. https://www.fda.gov/drugs/pharmaceutical-quality-resources/expiration-dates-questions-and-answers
This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.