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HealthRX.com · Printable question sheet

Ozempic at 18 to 29: thyroid, mood and pregnancy-plan follow-up sheet

Use this at the start and at each follow-up: the family and personal history that matters for Ozempic's thyroid warning, the symptoms to mention, a mood check, and your pregnancy plans. It keeps the label's stop and call rules on the same page.

Companion to “Ozempic Safety in Young Adults (18 to 29): What the Evidence Shows” · healthrx.com/ozempic/young-adult-safety · Facts checked 2026-10-19

History to give at the first visit

Family history of medullary thyroid cancer or MEN 2?
Thyroid nodules or past thyroid problems
Past depression, anxiety or thoughts of self-harm
Past pancreatitis or gallstones
Pregnancy plans in the next 12 months
Contraception you use now

Mention at each follow-up if you have had

  • A lump or swelling in the neck, hoarseness, trouble swallowing or shortness of breath
  • Low mood, losing interest in things, or thoughts of harming yourself
  • Vomiting or diarrhea most days
  • Pain in the upper stomach, fever, yellow skin or eyes, or pale stools
  • A missed period or a positive pregnancy test
  • Losing weight faster than your clinician expected

Follow-up visits

DateOzempic doseWeightMood check done?Stomach or bowel symptomsPlan

What the label and the studies on this page report

  • Ozempic must not be used with a personal or family history of medullary thyroid carcinoma or MEN 2; routine calcitonin tests or thyroid ultrasound are of uncertain value for spotting it early.[1]
  • In a French nested case-control study, 1 to 3 years of GLP-1 drug use was associated with higher risk of thyroid cancer (adjusted HR 1.58) and medullary thyroid cancer (1.78).[2]
  • In US health records of people with overweight or obesity, semaglutide prescriptions were associated with less first-time suicidal ideation over 6 months than other anti-obesity medicines (0.11% vs 0.43%; HR 0.27); an association, not proof of cause.[3]
  • Stop Ozempic at least 2 months before you plan to become pregnant.[1]

Act on these the way the Ozempic Medication Guide says

  • Lump or swelling in your neck, hoarseness, trouble swallowing or shortness of breath: tell your healthcare provider.[1]
  • Upper stomach pain, yellow skin or eyes, fever or clay-colored stools (possible gallbladder problems): tell your healthcare provider right away.[1]
  • Severe stomach pain that will not go away, with or without vomiting: stop Ozempic and call your healthcare provider right away.[1]
  • Swelling of the face, lips, tongue or throat, trouble breathing or swallowing, severe rash or itching, fainting or a very fast heartbeat: stop Ozempic and get medical help right away.[1]

Questions for your prescriber

  1. Does anything in my family or personal history make Ozempic a poor choice for me?
  2. How and when will my mood be checked while I take it?
  3. Which contraception is most reliable for me while my dose is changing?
  4. If I want to try for a baby, when should I stop, and what replaces Ozempic in that time?
  5. What should I do first if I find out I am pregnant?
Sources for the facts on this sheet
  1. Novo Nordisk, via DailyMed. Ozempic (semaglutide) injection, for subcutaneous use: prescribing information and Medication Guide. Effective 2026-06-01. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=adec4fd2-6858-4c99-91d4-531f5f2a2d79
  2. Bezin J, Gouverneur A, Pénichon M, et al. GLP-1 Receptor Agonists and the Risk of Thyroid Cancer. Diabetes Care 2023. PMID 36356111. https://pubmed.ncbi.nlm.nih.gov/36356111/
  3. Wang W, Volkow ND, Berger NA, et al. Association of semaglutide with risk of suicidal ideation in a real-world cohort. Nat Med 2024. PMID 38182782. https://pubmed.ncbi.nlm.nih.gov/38182782/

This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.