HealthRX.com · Printable supplement log
NMN or NR product: US status and quality record
Write down exactly which NMN or NR product you take, check its label and paperwork against FDA's current position, and keep a record of the questions you asked the seller and your clinician. The status facts come from FDA's own 2016 to 2025 letters and inventory.
Where the US record stands
- Since September 29, 2025, FDA's position is that NMN is not excluded from the dietary supplement definition.[1]
- On December 2, 2025, FDA set aside its October 11 and November 4, 2022 letters that had excluded NMN.[1]
- FDA acknowledging a new dietary ingredient notification is a procedural step, not a finding that the ingredient is safe.[1]
- A new dietary ingredient needs a notification to FDA at least 75 days before the product is sold.[2]
- FDA had no questions about GRAS notice 635 for nicotinamide riboside chloride (closed Aug 3, 2016), covering foods such as vitamin waters at up to 0.0057% by weight.[3]
The product you take
Product name and seller
Ingredient as written on the labelbeta-NMN, nicotinamide riboside chloride, or another form
Amount per serving and servings per day
Lot number and expiry date
Third-party certification shownand whether the certifier's own website lists it
Certificate of analysis: lab, date and purity result
Before relying on the label
- The ingredient form is named, not just 'NAD+ booster'
- The daily amount on the label is written down above
- A certificate of analysis for this lot was requested
- Any certification mark was checked on the certifier's own site
- Seller and country of origin noted
- Every product you take, including NR or NMN, is on your medication list
Questions for the seller or manufacturer
- Has a new dietary ingredient notification been filed for this NMN, and what NDI number did FDA assign?
- What daily amount did that notification cover, and does this product stay within it?
- Does the certificate of analysis cover this exact lot, and when was it tested?
- Was purity tested near the expiry date or only at manufacture?
Questions for your clinician
- Does NMN or NR interact with anything I take?
- Is there a reason to avoid it given my health conditions?
- Should I tell you before I start, change or stop it?
Products and changes
| Date | Product and lot | Daily amount | Why started, changed or stopped |
|---|---|---|---|
Sources for the facts on this sheet
- U.S. Food and Drug Administration. FDA letter to Inner Mongolia Kingdomway Pharmaceutical Limited regarding NDIN 1259, beta-nicotinamide mononucleotide (NMN). Accessed 2026-10-18. https://downloads.regulations.gov/FDA-2022-S-0023-0069/attachment_1.pdf
- U.S. Food and Drug Administration, Human Foods Program. FDA response to citizen petition FDA-2023-P-0872 on the regulatory status of beta-nicotinamide mononucleotide (NMN). Accessed 2026-10-18. https://downloads.regulations.gov/FDA-2023-P-0872-2754/attachment_1.pdf
- U.S. Food and Drug Administration. GRAS Notices: GRN No. 635, Nicotinamide riboside chloride. Accessed 2026-10-18. https://www.hfpappexternal.fda.gov/scripts/fdcc/index.cfm?set=GRASNotices&id=635
This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.