HealthRX.com · Printable side-effect diary
Mounjaro side-effect diary: your own record next to the trial numbers
Online posts tell you what other people felt; this diary records what you feel, day by day, so you and your prescriber can see whether symptoms follow your dose increases and settle. The trial and label figures on the sheet give a fair point of comparison.
Where you are in treatment
Date of first injection
Current dose and injection day
Date of the last dose increase
Other medicines started recently
Daily symptom record
Rate nausea and fatigue as none, mild, moderate or severe. Note the day of the week you inject so patterns after each injection show up.
| Date | Days since injection | Nausea | Vomiting (times) | Bowel movement or constipation | Burping or heartburn | Fatigue | Fluids and food today |
|---|---|---|---|---|---|---|---|
What the trials and labels recorded
- Mounjaro's placebo-controlled diabetes trials: nausea 12% to 18% on Mounjaro against 4% on placebo; diarrhea 12% to 17% against 9%; decreased appetite 5% to 11% against 1%; constipation 6% to 7% against 1%.[1]
- Most nausea, vomiting and diarrhea came while the dose was being raised and decreased over time.[1]
- Injection site reactions: 3.2% on Mounjaro against 0.4% on placebo.[1]
- In the heart outcomes trial, fatigue was reported by 10% and decreased appetite by 17% of Mounjaro-treated adults.[1]
- Zepbound weight-reduction trials: hair loss in 4% to 5% on tirzepatide against 1% on placebo, associated with weight reduction.[2]
Do not wait for your next visit
- Severe stomach pain that will not go away, sometimes reaching your back, with or without vomiting.[1]
- Swelling of the face, lips, tongue or throat, or trouble breathing or swallowing.[1]
- Upper stomach pain with fever, yellow skin or eyes, or clay-colored stools.[1]
- Nausea, vomiting or diarrhea that keeps going, which can dehydrate you and strain your kidneys.[1]
Questions to bring
- My symptoms flare after each increase. Should I stay on this dose longer before the next one?
- Is this symptom one the label lists, or should it be looked into separately?
- Could my tiredness come from eating or drinking too little?
- Is my hair shedding more likely linked to how fast my weight is falling?
- Which symptoms on this diary mean I should call you rather than wait?
Sources for the facts on this sheet
- Eli Lilly and Company, via DailyMed. Mounjaro (tirzepatide) injection, for subcutaneous use: prescribing information and Medication Guide. Effective 2026-08-27. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d2d7da5d-ad07-4228-955f-cf7e355c8cc0
- Eli Lilly and Company, via DailyMed. Zepbound (tirzepatide) injection, for subcutaneous use: prescribing information and Medication Guide. Effective 2026-08-28. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=487cd7e7-434c-4925-99fa-aa80b1cc776b
This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.