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HealthRX.com · Printable side-effect diary

Wegovy vomiting week-by-week diary

One line for each week of treatment: the dose, how many days you vomited and whether you kept fluids down, so you can see whether vomiting is following a dose step or lasting beyond it. Bring it to any call about delaying the next increase or about a missed injection.

Companion to “Vomiting on Wegovy (semaglutide 2.4 mg): Week-by-Week Timeline of What to Expect” · healthrx.com/side-effects-wegovy-vomiting/timeline · Facts checked 2026-10-19

Treatment start

Date of the first Wegovy injection
Injection day of the week
Current dose, and the week it started

Weekly record

Week 1 is the week of your first injection.

Week of treatmentDose that weekDays with vomitingMost episodes in one dayFluids kept down every day?Remedy or antiemetic usedNext step held or delayed?

What the label and the pooled trials show

  • The label's injection schedule starts at 0.25 mg in weeks 1 to 4 and reaches the maintenance dose from week 17.[1]
  • If a dose is not tolerated during escalation, the label says to consider delaying the next step for 4 weeks.[1]
  • Missed injection: if the next dose is more than 2 days away, inject as soon as possible; if it is less than 2 days away, skip the missed dose.[1]
  • After 2 or more missed doses in a row, the label says to restart escalation at a lower dose.[1]
  • In pooled STEP 1 to 3, vomiting was most common at about week 20, and one episode lasted a median of 2 days.[2]

Call now instead of waiting for the next step

  • Severe pain in your stomach area that will not go away, with or without vomiting: stop Wegovy and call your healthcare provider right away.[1]
  • Vomiting that does not go away: tell your healthcare provider right away; losing fluids can lead to kidney problems.[1]

For the call about the next dose

  1. Does my vomiting match the last dose step, or has it gone on beyond it?
  2. Should the next increase wait, and for how long?
  3. Is an antiemetic right for me, given my other medicines?
  4. What should I do with an injection that falls due during a vomiting spell?
Sources for the facts on this sheet
  1. Novo Nordisk, via DailyMed. Wegovy (semaglutide) injection and tablets: prescribing information and Medication Guide. Effective 2026-06-18. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=ee06186f-2aa3-4990-a760-757579d8f77b
  2. Wharton S, Calanna S, Davies M, et al. Gastrointestinal tolerability of once-weekly semaglutide 2.4 mg in adults with overweight or obesity, and the relationship between gastrointestinal adverse events and weight loss. Diabetes Obes Metab 2022. PMID 34514682. https://pubmed.ncbi.nlm.nih.gov/34514682/

This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.