HealthRX.com · Printable side-effect diary
Zepbound injection site log and call sheet
Record each weekly injection, where it went and what the skin did afterwards, measured in centimetres and dated, so a call about a lump, spreading redness or itching starts from facts. The label's allergy warning signs and site-rotation instructions sit on the same page.
Before you start the log
Current weekly dose (mg)
Devicesingle-dose pen, vial or KwikPen
Usual injection day
Past reactions to a GLP-1 or GIP medicine, or other drug allergies
Each weekly injection
Measure redness or a lump across its widest point. Photograph the site on the first day and again if it changes.
| Date | Dose (mg) | Area and spot (abdomen, thigh, upper arm) | What appeared (redness, itch, lump, bruise) | Widest size (cm) | Date it cleared | Photo? |
|---|---|---|---|---|---|---|
From the Zepbound label
- Use a different injection spot every week; staying in the same body area is fine as long as the exact spot changes.[1]
- In the weight trials, injection site reactions were reported by 6% to 8% of people on Zepbound and 2% on placebo.[1]
- People who developed antibodies to tirzepatide had site reactions and allergic-type reactions more often.[1]
- Zepbound should not be used after a serious allergic reaction to tirzepatide or any of its ingredients.[1]
Stop Zepbound and get medical help right away
- Swelling of your face, lips, tongue or throat, or problems breathing or swallowing.[1]
- Severe rash or itching, fainting or feeling dizzy, or a very rapid heartbeat.[1]
Have ready if a site reaction is not settling
- This log, with the size measured each day
- Photos from the first day and from today
- Whether it started after a dose increase
- Fever, pus, warmth or red streaks spreading from the site
- Hives or swelling away from the injection site
- Creams, cold compresses or antihistamines already tried
Questions for your prescriber
- Does this look like a local reaction, an infection or an allergy?
- Should I avoid this body area for a while?
- Is anything in my injection technique worth changing?
- Would a different device or formulation make sense for me?
- If it has not cleared, when should I call back or be seen?
Sources for the facts on this sheet
- Eli Lilly and Company, via DailyMed. Zepbound (tirzepatide) injection, for subcutaneous use: prescribing information and Medication Guide. Effective 2026-08-28. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=487cd7e7-434c-4925-99fa-aa80b1cc776b
This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.