HealthRX.com · Printable symptom log
Zepbound nausea call sheet: fluids, warning signs and what to tell the clinic
Use this when nausea is worse than expected: write down your dose history, then log every few hours what fluids stayed down, how dark your urine is and where any pain sits. The label's reasons to call your provider right away, including the pain that means stopping Zepbound, are printed alongside, with questions to ask on the call.
Before you call
Current dose and date of last injection
Date of your last dose increase
When this bout of nausea started
Times you vomited in the last 24 hours
Last time you kept fluids down
Other medicineswater pills, blood pressure medicines, anti-inflammatory pain relievers
Every few hours
| Time | Fluids kept down (cups) | Vomited? | Urine: pale, dark or none | Pain 0-10 and where | Dizzy on standing? |
|---|---|---|---|---|---|
Call your healthcare provider right away
- Severe stomach pain that will not go away, with or without vomiting; it may spread to your back. The label says to stop Zepbound and call right away.[1]
- Upper stomach pain with fever, yellow skin or eyes, or clay-colored stools: possible gallbladder trouble.[1]
- Nausea, vomiting or diarrhea that does not go away: the fluid loss can cause kidney problems.[1]
Label numbers to keep this in proportion
- Nausea was reported by 25% to 29% of people on Zepbound in the weight trials and by 8% on placebo.[1]
- Most nausea, vomiting and diarrhea happened while the dose was being increased, then became less frequent.[1]
- Drinking fluids helps lower the chance of dehydration.[1]
Questions for the call
- Should I take my next dose, or hold it?
- Do I need blood tests today, such as lipase or kidney function?
- Is an anti-nausea medicine suitable for me?
- Should my dose go back a step for now?
- What would mean I should go to urgent care tonight?
Sources for the facts on this sheet
- Eli Lilly and Company, via DailyMed. Zepbound (tirzepatide) injection, for subcutaneous use: prescribing information and Medication Guide. Effective 2026-08-28. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=487cd7e7-434c-4925-99fa-aa80b1cc776b
This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.