HealthRX.com · Printable question sheet
Zepbound vomiting that has not settled: visit and workup sheet
Bring your dose history, a count of vomiting days and what you have already tried, then use the questions to agree on tests and a dose plan. The label's stop-and-call warnings are printed so they are not missed while you wait for the appointment.
Dose history
Current Zepbound dose (mg)
Date of the last dose increase
Weeks at this dose
Date of the last injection
Missed, delayed or doubled doses
Vomiting days
One line for each day you vomited.
| Date | Times vomited | Kept fluids down? | Pain, and where | Antiemetic taken | Urine color |
|---|---|---|---|---|---|
Already tried
- Smaller, low-fat meals
- Sipping fluids through the day
- An oral rehydration solution
- An antiemetic prescribed for me
- Staying longer on the current dose step
- A lower dose
From the Zepbound label
- In the weight-reduction trials, most nausea, vomiting and diarrhea happened during dose escalation and decreased over time.[1]
- Tirzepatide slows stomach emptying; the delay is largest after the first dose and diminishes over time.[1]
- In two weight-reduction trials, severe stomach and bowel reactions were reported in 1.7%, 2.5% and 3.1% on 5, 10 and 15 mg, against 1% on placebo.[1]
- Zepbound is not recommended in severe gastroparesis.[1]
Questions for the visit
- Which tests come first: blood chemistry, lipase, an ultrasound or a gastric emptying scan?
- Could a gallbladder or pancreas problem explain this?
- Should I stay at this dose, step down or pause, and for how long?
- Is an antiemetic appropriate for me, and which side effects should I watch for?
- At what point would you move me to a different medicine?
Stop and call; do not wait for the visit
- Severe pain in your stomach area that will not go away, with or without vomiting: stop Zepbound and call your healthcare provider right away.[1]
- Nausea, vomiting or diarrhea that does not go away: tell your healthcare provider right away. Losing fluids can cause kidney problems.[1]
- Upper stomach pain, fever, yellowing of the skin or eyes, or clay-colored stools: tell your healthcare provider right away.[1]
Sources for the facts on this sheet
- Eli Lilly and Company, via DailyMed. Zepbound (tirzepatide) injection, for subcutaneous use: prescribing information and Medication Guide. Effective 2026-08-28. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=487cd7e7-434c-4925-99fa-aa80b1cc776b
This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.