HealthRX.com · Printable medication review sheet
Ozempic and calcium: supplement and timing check sheet
Write down the calcium product you use, the medicines that set its timing, and a week of actual dose times. The fact panel lists what each label and study says, so a pharmacist can check the plan at a glance.
Your calcium supplement
Product name
Formcarbonate, citrate or other
Calcium per tablet (mg)from the Supplement Facts panel
Tablets per dose and doses per day
Vitamin D in the same product? Amount
Medicines that set the timing
Levothyroxine: dose and time taken
Alendronate or another bisphosphonate: day and time
Acid reducer (PPI or H2 blocker), if any
Ozempic injection day
One week of real times
| Day | Levothyroxine | Bisphosphonate | First meal | Calcium dose 1: time and mg | Calcium dose 2: time and mg | Stomach symptoms |
|---|---|---|---|---|---|---|
What the labels and studies say
- Ozempic's label: inject once weekly on the same day, at any time of day, with or without meals. The label does not mention calcium.[1]
- In Ozempic's clinical pharmacology trials, semaglutide did not affect absorption of oral medicines to any clinically relevant degree.[1]
- Synthroid's label: take levothyroxine at least 4 hours apart from phosphate binders such as calcium carbonate.[2]
- Fosamax's label: calcium supplements interfere with alendronate absorption; take it at least 30 minutes before the first food, drink or medicine of the day.[3]
- In 20 people on long-term levothyroxine, 1,200 mg a day of calcium as carbonate taken with it for 3 months raised average TSH from 1.6 to 2.7 mIU/L, and 20% went above the normal range.[4]
- MedlinePlus: calcium is absorbed best in amounts of no more than 500 mg at a time, and 2,000 mg a day from food and supplements is considered safe above age 50.[5]
Questions for the pharmacist
- Is my product carbonate or citrate, and does that change when I take it?
- How far apart should my calcium and levothyroxine be?
- On my alendronate day, when can I take calcium?
- Should my TSH be rechecked now that I started or changed calcium?
- Does my total from food and supplements go over the safe amount for my age?
Sources for the facts on this sheet
- Novo Nordisk, via DailyMed. Ozempic (semaglutide) injection, for subcutaneous use: prescribing information and Medication Guide. Effective 2026-06-01. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=adec4fd2-6858-4c99-91d4-531f5f2a2d79
- AbbVie Inc., via DailyMed. Synthroid (levothyroxine sodium) tablets, for oral use: prescribing information. Effective 2024-02-20. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1e11ad30-1041-4520-10b0-8f9d30d30fcc
- Organon LLC, via DailyMed. Fosamax (alendronate sodium) tablets and oral solution: prescribing information. Effective 2026-03-12. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=14e931fd-2c5f-4d90-b7db-5980706f4a56
- Singh N, Singh PN, Hershman JM. Effect of calcium carbonate on the absorption of levothyroxine. JAMA 2000. PMID 10838651. https://pubmed.ncbi.nlm.nih.gov/10838651/
- U.S. National Library of Medicine (MedlinePlus). Calcium in diet: MedlinePlus Medical Encyclopedia. Accessed 2026-10-18. https://medlineplus.gov/ency/article/002412.htm
This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.