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Vitamin D on Zepbound: product, daily total and meal record
List every product that contains vitamin D, add up the daily total in IU, and note whether you took it with a meal that had some fat and whether nausea got in the way. Space for any 25(OH)D result and the reason it was ordered is included, with the reference numbers it can be compared against.
Every product that contains vitamin D
Multivitamins and calcium tablets often contain vitamin D too.
Product 1: name, D2 or D3, amount per dose (IU or mcg)
Product 2: name, D2 or D3, amount per dose
Prescription vitamin D, if any: dose and how often
Total from all products on a usual day (IU)
One week
| Date | Products and amounts taken | Taken with a meal that had some fat? | Nausea or vomiting that day | Day's total (IU) |
|---|---|---|---|---|
Reference numbers
- Recommended daily amount: 600 IU (15 mcg) for adults 19 to 70 and 800 IU (20 mcg) over 70. Safe upper limit: 4,000 IU (100 mcg) a day from age 9.[1]
- To convert micrograms to IU, multiply by 40.[1]
- Blood 25(OH)D: below 12 to 20 ng/mL is too low, 20 ng/mL or above is enough for most people, and above 50 ng/mL is probably too high.[1]
- Too much vitamin D can raise blood calcium, with confusion, kidney damage or stones, nausea, vomiting, constipation, poor appetite, weakness and weight loss; several of these overlap with Zepbound side effects.[1]
- In 50 healthy older adults given one 50,000 IU dose of D3, the 12-hour blood level was 32% higher with a meal containing fat than with a fat-free meal.[2]
- The Endocrine Society's current vitamin D guideline suggests against routine vitamin D blood tests without an established reason, including in people with obesity.[3]
If a 25(OH)D test is done
Date and result, with unitsng/mL or nmol/L
Why it was ordered
Plan agreed after the result
For your Zepbound prescriber
- Do I have a specific reason, such as osteoporosis or a past bariatric operation, for more vitamin D than the daily recommended amount?
- Is a vitamin D blood test needed for me, and what would we do with the result?
- Is my total from all products under the safe upper limit?
- If nausea makes me skip doses, does that matter for me?
Sources for the facts on this sheet
- U.S. National Library of Medicine (MedlinePlus). Vitamin D: MedlinePlus Medical Encyclopedia. Accessed 2026-10-19. https://medlineplus.gov/ency/article/002405.htm
- Dawson-Hughes B, Harris SS, Lichtenstein AH, et al. Dietary fat increases vitamin D-3 absorption. J Acad Nutr Diet 2015. PMID 25441954. https://pubmed.ncbi.nlm.nih.gov/25441954/
- Demay MB, Pittas AG, Bikle DD, et al. Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2024. PMID 38828931. https://pubmed.ncbi.nlm.nih.gov/38828931/
This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.