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HealthRX.com · Printable symptom log

Injection site reaction tracker with measurements and warning signs

Note the product, its source and lot, then check the site twice a day: how wide the redness is, whether it has crossed a pen line, and any warmth, drainage, itching or fever. Emergency and same-day warning signs from MedlinePlus are printed beside the log, with questions for the clinician.

Companion to “Peptide Injection Site Reactions: What Could Be Causing Them and How to Treat Them” · healthrx.com/symptoms-peptide-injection-site-reaction/differential · Facts checked 2026-10-18

The product and the injection

Product name and who prescribed or supplied it
FDA-approved product, compounded, or other
Lot number and expiry or beyond-use date
Needle size and the site used
Date and time of the injection

Morning and evening checks of the site

Draw around the edge of the redness with a pen at the first check, then measure across its widest point each time.

Date and timeRedness across (cm)Still inside the pen line?Warm, painful or draining?Itch or hivesTemperaturePhoto?

Call 911: possible anaphylaxis

  • Difficulty breathing, wheezing, or trouble swallowing.[1]
  • Swelling of the face, eyes or tongue.[1]
  • Hives with dizziness or light-headedness, or loss of consciousness. These symptoms often come on within seconds or minutes.[1]

Contact a provider right away: possible skin infection

  • Redness that gets bigger, with pain or tenderness, or fever with chills.[2]
  • Red streaks spreading from the area, or blisters over it.[2]
  • Drainage of any kind, fever, pain, redness or swelling at the site.[3]

From approved peptide labels

  • Tesamorelin (Egrifta): site reactions in 25% of people on the drug and 14% on placebo in the first 26 weeks.[4]
  • Semaglutide (Wegovy): rotate injection sites with each dose.[5]

Questions for the clinician

  1. Does this look like irritation, infection or an allergy?
  2. Should I stop injecting until it has been checked?
  3. Could the product, its diluent or the way it was stored be the cause?
  4. If there is pus, should a sample be taken?
  5. How do I report this reaction, and to whom?
Sources for the facts on this sheet
  1. U.S. National Library of Medicine. Anaphylaxis: MedlinePlus Medical Encyclopedia. Accessed 2026-10-18. https://medlineplus.gov/ency/article/000844.htm
  2. U.S. National Library of Medicine. Cellulitis: MedlinePlus Medical Encyclopedia. Accessed 2026-10-18. https://medlineplus.gov/ency/article/000855.htm
  3. U.S. National Library of Medicine. Skin abscess: MedlinePlus Medical Encyclopedia. Accessed 2026-10-18. https://medlineplus.gov/ency/article/000863.htm
  4. Theratechnologies Inc., via DailyMed. Egrifta SV (tesamorelin) for injection, for subcutaneous use: prescribing information. Effective 2026-07-29. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3d783378-b02d-4f19-99dd-0fc91a042224
  5. Novo Nordisk, via DailyMed. Wegovy (semaglutide) injection and tablets: prescribing information. Effective 2026-06-18. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ee06186f-2aa3-4990-a760-757579d8f77b

This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.