HealthRX.com · Printable titration log
Ozempic restart titration log
Track a restart week by week: the date and dose of each injection, stomach symptoms, fluids and glucose, against the label's actual dose steps, so the decision to step up rests on your own record.
Before the first restart dose
Date of your last Ozempic injection
Dose at that injection (mg)
Why the break happened
Restart dose your prescriber chose (mg)
Insulin or sulfonylurea doses now
The label's dose steps (Ozempic has no 1.7 mg step)[1]
In type 2 diabetes with chronic kidney disease, the label's maintenance dose is 1 mg.
| Step | Weekly dose | When the label allows it |
|---|---|---|
| Start | 0.25 mg | for 4 weeks |
| Next | 0.5 mg | after 4 weeks on 0.25 mg |
| If more glucose control is needed | 1 mg | after at least 4 weeks on 0.5 mg |
| If still more is needed | 2 mg (maximum) | after at least 4 weeks on 1 mg |
Weekly restart record
| Week | Date | Dose (mg) | Nausea (none, mild, severe) | Vomiting episodes | Drinking normally? | Glucose |
|---|---|---|---|---|---|---|
Label points that bear on a restart
- Most nausea, vomiting and diarrhea in the trials happened during dose escalation.[1]
- Nausea in placebo-controlled trials: 15.8% on 0.5 mg and 20.3% on 1 mg, against 6.1% on placebo.[1]
- With insulin or a sulfonylurea, low blood sugar is more likely; the label suggests considering lower doses of those when Ozempic is started.[1]
- A missed dose can be taken within 5 days; after that, skip it and keep your usual day.[1]
Stop and call your prescriber for
- Persistent or severe stomach pain, sometimes into the back, with or without vomiting.[1]
- Nausea, vomiting or diarrhea that will not settle: fluid loss can cause kidney problems.[1]
Questions for the prescriber
- Do I restart at 0.25 mg or higher, and why?
- When will we decide whether to step up?
- Should my insulin or sulfonylurea dose change for the restart?
Sources for the facts on this sheet
- Novo Nordisk, via DailyMed. Ozempic (semaglutide) injection, for subcutaneous use: prescribing information and Medication Guide. Effective 2026-06-01. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=adec4fd2-6858-4c99-91d4-531f5f2a2d79
This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.