Back to the article

HealthRX.com · Printable lab tracker

Zepbound lab and visit planner for adults 30 to 49

A one-page grid for the tests your clinician orders before the first dose and at months 3, 6 and 12, with vitals for each visit, what the label reports about routine results, and the symptoms that should not wait for the next blood draw.

Companion to “Zepbound Monitoring for Adults (30 to 49): Lab Tests, Timelines, and What Your Doctor Should Track” · healthrx.com/zepbound/adult-monitoring · Facts checked 2026-10-18

Results by visit

Write each result with the lab's reference range. Your clinician decides which tests you need; blank rows are for anything added.

TestBefore first doseMonth 3Month 6Month 12
HbA1c
Lipid panel
Creatinine and eGFR
ALT and AST
Lipase
TSH

At each visit

Weight and percent change from the start
Resting heart rate
Blood pressure
Medicines started, stopped or changed

What the label reports about routine checks

  • On average lipase rose 28% to 35% and pancreatic amylase 20% to 25% in the weight trials; without other signs of pancreatitis the label calls their meaning unknown.[1]
  • Resting heart rate rose by a mean of 1 to 3 beats per minute.[1]
  • Gallstones: 1.1% on Zepbound versus 1% on placebo; gallbladder inflammation: 0.7% versus 0.2%.[1]
  • Birth control pills: switch to a non-oral method, or add a barrier method, for 4 weeks after starting and for 4 weeks after each dose increase.[1]
  • Routine calcitonin tests or thyroid ultrasound are of uncertain value for finding medullary thyroid cancer early.[1]

Report these without waiting for the next lab visit

  • Pain in the upper stomach, fever, yellowing of the skin or eyes, or clay-colored stools.[1]
  • Severe stomach pain that will not go away, sometimes spreading to the back.[1]
  • Nausea, vomiting or diarrhea that does not go away.[1]

Questions for the visit

  1. Which of these tests do I need, and what would each change?
  2. If my lipase comes back high but I feel well, what happens next?
  3. Does my contraception need to change around my dose steps?
  4. Which result would make you hold my next dose increase?
Sources for the facts on this sheet
  1. Eli Lilly and Company, via DailyMed. Zepbound (tirzepatide) injection, for subcutaneous use: prescribing information and Medication Guide. Effective 2026-08-28. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=487cd7e7-434c-4925-99fa-aa80b1cc776b

This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.