HealthRX.com · Printable medication review sheet
Zepbound medicine-by-medicine review for the prescriber or pharmacist
List every medicine and supplement once, mark how each is taken and whether it needs level checks, and note who will watch it while the Zepbound dose rises. The label works by category, so this sheet turns its rules into a checklist for your own list.
Every medicine and supplement you take
| Name and dose | By mouth? | Insulin or sulfonylurea? | Needs level or lab checks? | When taken, relative to meals | Who watches it | Next check |
|---|---|---|---|---|---|---|
The label's rules, by category
- Zepbound delays gastric emptying and may change how oral medicines are absorbed.[1]
- Oral medicines that depend on a threshold level or have a narrow therapeutic index, such as warfarin, should be monitored when Zepbound is added.[1]
- With insulin or a sulfonylurea, the prescriber should consider lowering that dose at the start. In the diabetes trial, low blood sugar affected 10.3% of patients on a sulfonylurea against 2.1% without one.[1]
- Birth control pills: switch to a non-oral method or add a barrier method for 4 weeks after starting and after each dose increase.[1]
- Laboratory studies showed low potential for tirzepatide to inhibit or induce CYP enzymes.[1]
Bring to the review
- Every prescription medicine, with doses
- Over-the-counter pain relievers, sleep aids and antacids
- Vitamins, minerals and herbal products
- The birth control method you use, if any
- Your Zepbound dose and the date of the next increase
Questions to ask
- Which of my medicines need a level or lab check after I start or increase Zepbound?
- Should I change the time I take any tablet relative to meals?
- Do any of my medicines tend to cause weight gain, and is there an alternative worth discussing?
- Who adjusts my insulin or sulfonylurea if my blood sugar runs low?
Act the same day if
- You take insulin or a sulfonylurea and feel dizzy, sweaty, confused or shaky: these can be low blood sugar.[1]
- Vomiting or diarrhea keeps fluids from staying down: dehydration can harm the kidneys.[1]
Sources for the facts on this sheet
- Eli Lilly and Company, via DailyMed. Zepbound (tirzepatide) injection, for subcutaneous use: prescribing information and Medication Guide. Effective 2026-08-28. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=487cd7e7-434c-4925-99fa-aa80b1cc776b
This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.