AndroGel Skin Irritation: Supplements With the Best Evidence
At a glance
- Supplements tested for AndroGel skin irritation / none identified
- Skin irritation in the AndroGel 1% study / mild local irritation in 12 of 163 men, treatment up to 42 months [1]
- Stopped treatment for irritation / 1 of 163 men [1]
- Teva testosterone gel 1% label, interactions listed / insulin, oral anticoagulants, corticosteroids or ACTH [2]
What the AndroGel study reports about skin irritation
The AndroGel result on skin irritation comes from a study of 163 hypogonadal men who applied 5, 7.5 or 10 g of AndroGel 1% daily for up to 42 months [1]. Mild local skin irritation occurred in 12 of them, and it led to discontinuation in only one. The study was not placebo controlled [1]. Its summary describes the irritation as mild but gives no separate figures for redness and does not describe any treatment for it [1].
What the interaction section of a testosterone gel label covers
The Teva testosterone gel 1% label is for a different product from AndroGel, so it is not AndroGel's own label. Its drug interactions section covers insulin, oral anticoagulants such as warfarin, and corticosteroids or ACTH, and it names no supplement [2].
Frequently asked questions
Do any supplements help with AndroGel skin irritation?
No study of a supplement for AndroGel skin irritation could be identified. In the AndroGel 1% study that followed 163 men for up to 42 months, mild local skin irritation occurred in 12 of them and one stopped treatment because of it [1].
How common is skin irritation with AndroGel?
In a study of 163 hypogonadal men applying 5, 7.5 or 10 g of AndroGel 1% daily for up to 42 months, 12 had mild local skin irritation [1].
Did anyone stop AndroGel because of skin irritation?
One of the 163 men in that study discontinued treatment because of mild local skin irritation [1].
Is AndroGel skin irritation serious?
In the AndroGel 1% study, the skin irritation was described as mild, and one man out of 163 stopped treatment [1].
What interactions does the testosterone gel 1% label cover?
The Teva testosterone gel 1% label, a different product from AndroGel, covers insulin, oral anticoagulants such as warfarin, and corticosteroids or ACTH. It names no supplement [2].
References
- Wang C, Cunningham G, Dobs A, Iranmanesh A, Matsumoto AM, Snyder PJ, et al. Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men. J Clin Endocrinol Metab. 2004;89(5):2085-98. Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men
- U.S. National Library of Medicine, DailyMed. Testosterone gel 1% topical (Teva) prescribing information. Testosterone gel 1% topical (Teva) label